<?xml version="1.0" encoding="UTF-8"?>
<!-- Created by Gepasi 3.30 on September 03, 2002, 23:25 -->
<sbml xmlns="http://www.sbml.org/sbml/level1" level="1" version="1">
	<model name="Linear_pathway_of_isomerisations__open_system_">
		<notes>
			<body xmlns="http://www.w3.org/1999/xhtml">
				<p>a -&gt; b -&gt; c -&gt; d -&gt; e -&gt; f</p>
				<p>all steps follow reversible mass action kinetics, a &amp; f are external metabolites</p>
				<p></p>
				<p>Here we scan the initial concentration of a, and the rate constant of the first </p>
				<p>step, keeping the equilibrium constant equal to 1 (see links). Follow the </p>
				<p>progress of the 300 simulations on the Scan page.</p>
			</body>
		</notes>
		<listOfCompartments>
			<compartment name="compartment" volume="1"/>
		</listOfCompartments>
		<listOfSpecies>
			<specie name="a" compartment="compartment" initialAmount="1" boundaryCondition="true"/>
			<specie name="b" compartment="compartment" initialAmount="0" boundaryCondition="false"/>
			<specie name="c" compartment="compartment" initialAmount="0" boundaryCondition="false"/>
			<specie name="d" compartment="compartment" initialAmount="0" boundaryCondition="false"/>
			<specie name="e" compartment="compartment" initialAmount="0" boundaryCondition="false"/>
			<specie name="f" compartment="compartment" initialAmount="0.1" boundaryCondition="true"/>
		</listOfSpecies>
		<listOfRules>
			<parameterRule name="k2_1" type="scalar" formula="k1_1"/>
		</listOfRules>
		<listOfReactions>
			<reaction name="R1" reversible="true">
				<listOfReactants>
					<specieReference specie="a" stoichiometry="1"/>
				</listOfReactants>
				<listOfProducts>
					<specieReference specie="b" stoichiometry="1"/>
				</listOfProducts>
				<kineticLaw formula="k1_1*a-k2_1*b">
					<listOfParameters>
						<parameter name="k1_1" value="1"/>
						<parameter name="k2_1" value="2.022875890320557"/>
					</listOfParameters>
				</kineticLaw>
			</reaction>
			<reaction name="R2" reversible="true">
				<listOfReactants>
					<specieReference specie="b" stoichiometry="1"/>
				</listOfReactants>
				<listOfProducts>
					<specieReference specie="c" stoichiometry="1"/>
				</listOfProducts>
				<kineticLaw formula="k1_2*b-k2_2*c">
					<listOfParameters>
						<parameter name="k1_2" value="1"/>
						<parameter name="k2_2" value="1"/>
					</listOfParameters>
				</kineticLaw>
			</reaction>
			<reaction name="R3" reversible="true">
				<listOfReactants>
					<specieReference specie="c" stoichiometry="1"/>
				</listOfReactants>
				<listOfProducts>
					<specieReference specie="d" stoichiometry="1"/>
				</listOfProducts>
				<kineticLaw formula="k1_3*c-k2_3*d">
					<listOfParameters>
						<parameter name="k1_3" value="1"/>
						<parameter name="k2_3" value="1"/>
					</listOfParameters>
				</kineticLaw>
			</reaction>
			<reaction name="R4" reversible="true">
				<listOfReactants>
					<specieReference specie="d" stoichiometry="1"/>
				</listOfReactants>
				<listOfProducts>
					<specieReference specie="e" stoichiometry="1"/>
				</listOfProducts>
				<kineticLaw formula="k1_4*d-k2_4*e">
					<listOfParameters>
						<parameter name="k1_4" value="1"/>
						<parameter name="k2_4" value="1"/>
					</listOfParameters>
				</kineticLaw>
			</reaction>
			<reaction name="R5" reversible="true">
				<listOfReactants>
					<specieReference specie="e" stoichiometry="1"/>
				</listOfReactants>
				<listOfProducts>
					<specieReference specie="f" stoichiometry="1"/>
				</listOfProducts>
				<kineticLaw formula="k1_5*e-k2_5*f">
					<listOfParameters>
						<parameter name="k1_5" value="1"/>
						<parameter name="k2_5" value="1"/>
					</listOfParameters>
				</kineticLaw>
			</reaction>
		</listOfReactions>
	</model>
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